ERCC1/RAD10 (Tumor Progression Marker) Antibody MBS4380871 from MyBioSource.com

Product Specs
ItemERCC1/RAD10 (Tumor Progression Marker) Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380871
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ApplicationsELISA (EIA), Western Blot (WB)
SpeciesMouse
ReactivityHuman (Hu)
IsotypeIgG1 kappa
CloneERCC1/2683
Conjugate/TagUnconjugated
NCBI Gene AliasesRAD10, COFS4, UV20
NCBI Full Gene NameERCC excision repair 1, endonuclease non-catalytic subunit
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
TargetERCC1/RAD10
Molecular Weight110kDa
Format200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml

Specifications/Features

Recognizes a protein of 110kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer

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