MyBioSource.com's Mouse Anti Rabbit MHC Class II DQ Antibody is a Mouse monoclonal antibody. It reacts with Rabbit. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - frozen, and Immunoprecipitation.
Description
Mouse anti rabbit MHC class II monoclonal antibody, clone 2C4 recognizes the class II RLA-DQ molecule. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rabbits, this complex is referred to as the rabbit leukocyte antigen (RLA) region. There are 3 major MHC class II proteins encoded by the RLA which are RLA DP, RLA DQ and RLA DR.
Mouse anti rabbit MHC class II recognizes the RLA DQ molecule, expressed by antigen presenting cells, B cells and monocytes.
This antibody is reported to inhibit the mixed lymphocyte reaction by 80%. Immunoprecipitation studies yield three bands of molecular weight 28, 31 and 35 kDa