Rabbit Anti-Elastin Antibody MBS4380548 from MyBioSource.com

Product Specs
ItemRabbit Anti-Elastin Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380548
ClonalityMonoclonal
ReactivityHuman. Others not known
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunohistology (Formalin-Fixed)
SpeciesRabbit
Molecular Weight70kDa
TargetElastin (ELN)
NCBI Full Gene Nameelastin
NCBI Gene AliasesSVAS, WS, WBS, ADCL1
Conjugate/TagUnconjugated
CloneELN/3131R
IsotypeIgG
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)

Specifications/Features

Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension

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