MyBioSource.com's Anti-CD45 Rabbit Monoclonal Antibody is a Rabbit monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity)