The Netrin-1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The Netrin-1 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Function: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Subunit Structure: Binds to its receptors; DCC, DSCAM, UNC5A, UNC5B, UNC5C and probably UNC5D