The RSPO1 Antibody - middle region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The RSPO1 Antibody - middle region has been shown to work in the following applications: Western Blot.
Description
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants