Rabbit Anti-Ferritin, Light Chain Antibody MBS439983 from MyBioSource.com

Product Specs
ItemRabbit Anti-Ferritin, Light Chain Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS439983
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ReactivityHuman. Others not known
ApplicationsImmunohistochemistry (IHC) Formalin
Molecular Weight19-25kDa
TargetFerritin, Light Chain (FTL)
NCBI Full Gene Nameferritin light chain
NCBI Gene AliasesNBIA3, LFTD
CloneFTL/2338R
IsotypeIgG
Conjugate/TagUnconjugated
SpeciesRabbit
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ClonalityMonoclonal

Specifications/Features

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts

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