Rabbit Anti-Langerin/CD207 Antibody MBS4381143 from MyBioSource.com

Product Specs
ItemRabbit Anti-Langerin/CD207 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381143
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ReactivityHuman
Format200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsELISA (EIA)
SpeciesRabbit
Molecular Weight48kDa
TargetLangerin/CD207
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
NCBI Full Gene NameCD207 molecule
NCBI Gene AliasesCLEC4K
Conjugate/TagUnconjugated
IsotypeIgG
CloneLGRN/3136R

Specifications/Features

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein

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