MyBioSource.com's CASP9 Antibody is a Rabbit monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunofluorescence, and Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP)