Rabbit Anti-NKX2.2 Antibody MBS4380141 from MyBioSource.com

Product Specs
ItemRabbit Anti-NKX2.2 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380141
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ReactivityHuman. Others not known
Molecular Weight40-50kDa
NCBI Gene AliasesNKX2.2, NKX2B
IsotypeIgG
CloneNX2/2198R
ApplicationsFCM, IF, IHC-p
Conjugate/TagUnconjugated
NCBI Full Gene NameNK2 homeobox 2
TargetNKX2.2
SpeciesRabbit
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml

Specifications/Features

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors

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