MyBioSource.com's Anti-Bax Rabbit Monoclonal Antibody is a Rabbit monoclonal antibody. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunohistochemistry.
Description
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis