The Anti-USP14 Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-USP14 Rabbit Monoclonal Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs)