Rabbit Anti-CFTR Antibody MBS439858 from MyBioSource.com

Product Specs
ItemRabbit Anti-CFTR Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS439858
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ReactivityHuman. Others not known
Format200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC) Formalin
SpeciesRabbit
Molecular Weight165-170kDa
TargetCFTR (Cystic Fibrosis Transmembrane Conductance Regulator)
NCBI Full Gene Namecystic fibrosis transmembrane conductance regulator
NCBI Gene AliasesTNR-CFTR, ABC35, CFTR/MRP, CF, dJ760C5.1, ABCC7, MRP7
Conjugate/TagUnconjugated
IsotypeIgG
CloneCFTR/1775R

Specifications/Features

Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation

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