Rabbit Anti-VLDL-Receptor Antibody MBS4381339 from MyBioSource.com

Product Specs
ItemRabbit Anti-VLDL-Receptor Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4381339
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ReactivityHuman, Rat
ApplicationsELISA (EIA)
TargetVLDL-Receptor (Very Low Density Lipoprotein Receptor)
NCBI Full Gene Namevery low density lipoprotein receptor
IsotypeIgG
CloneVLDLR/2896R
Conjugate/TagUnconjugated
NCBI Gene AliasesVLDL-R, CHRMQ1, CAMRQ1, VLDLRCH, CARMQ1
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Molecular Weight143-161kDa
SpeciesRabbit
Format200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ClonalityMonoclonal

Specifications/Features

VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development

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