SorCS2 Antibody AF4238 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSorCS2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF4238
ReactivityHuman
Conjugate/TagUnconjugated
HostSheep
IsotypeIgG
ApplicationsImmunohistochemistry,Western Blot,Immunocytochemistry,ELISA Detection
TargetSorCS2
Quantity100 ug (also 25 ug)
NCBI Full Gene Namesortilin related VPS10 domain containing receptor 2
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenNS0-derived recombinant human SorCS2, Ser70-Gly1078, Accession # Q96PQ0
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human SorCS2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse (rm) SorCS2 is observed and less than 1% cross-reactivity with recombinant human (rh) SorCS1 and rhSorCS3 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activityMolecular PsychiatryMarch 1, 2026Mathias Kaas, Sarah Broholt Dinesen, Ole Ahlgreen, Peder Madsen, Simon Mølgaard, Anders Dalby, Camilla Gustafsen, Ditte Olsen, Jinjie Duan, Joachim Vilstrup, et al.(Roche)). Antisera against SorCS2 (F7100), SorCS2 ICD, and SorCS3 were custom made from DAKO. α-SorCS2 (AF4238) were from R&D Systems (used for western blot analysis of iPSC-derived neurons), α-FLAG tag M2 (B3111),

(2) Human CLOCK enhances neocortical functionNature NeuroscienceAugust 1, 2025Yuxiang Liu, Miles R. Fontenot, Ashwinikumar Kulkarni, Nitin Khandelwal, Seon Hye E. Voth Park, Connor Criswell, Matthew Harper, Pin Xu, Nisha Gupta, Jay R. Gibson, et al.We used sheep anti-TENM2 (1:100, Invitrogen, #PA5-47638) and sheep anti-SORCS2 (1:500; R&D Systems, #AF4238) to stain the two proteins, and mouse anti-CAMKII (1:100; Abcam, #ab22609) for excitatory neurons in

(3) Loss of SORCS2 is Associated with Neuronal DNA Double-Strand BreaksCellular and molecular neurobiologyJanuary 1, 2023Gospodinova KO, Olsen D, Kaas M, Anderson SM, Phillips J, Walker RM, Bermingham ML, Payne AL, Giannopoulos P, Pandya D, et al.Methods Compounds and Antibodies Primary antibodies used in this study: polyclonal sheep anti-SORCS2 (AF4238, R&D Systems), monoclonal mouse anti-γH2A.X (JBW301, Millipore) and polyclonal rabbit anti-53BP1 (NB100304,

(4) Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retentionCommunications biologyOctober 5, 2021Vignoli B, Sansevero G, Sasi M, Rimondini R, Blum R, Bonaldo V, Biasini E, Santi S, Berardi N, Lu B, et al.mouse α-PSD95 (Merck-Millipore Cat#MAB1596; RRID:AB_2092365, IHC 1:500), sheep α-SorCS2 (R&D System Cat#AF4238; RRID:AB_10645642), rabbit α-SorCS2 (MyBioSource Cat# MBS5302436), rabbit α-p75NTR (Promega Cat#G3231;

(5) SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's diseaseJCI insightMay 4, 2017Ma Q, Yang J, Milner TA, Vonsattel JG, Palko ME, Tessarollo L, Hempstead BL.to recover antigenic epitopes. Slides were probed with sheep anti–human SorCS2 (R&D Systems, catalog AF4238). Bound antibodies were detected with a biotinylated-conjugated secondary antibody system (Jackson ImmunoResearch

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SorCS2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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SorCS2 Antibody from R&D Systems, a Bio-Techne Brand

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