Rabbit Anti-IgM Antibody MBS4380600 from MyBioSource.com

Product Specs
ItemRabbit Anti-IgM Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380600
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
Molecular Weight50-75kDa
TargetIgM (Immunoglobulin Mu Heavy Chain)
NCBI Full Gene Nameimmunoglobulin heavy constant mu
NCBI Gene AliasesAGM1, MU, VH
Conjugate/TagUnconjugated
ReactivityHuman (Hu)
CloneIGHM/2559R
IsotypeIgG
ApplicationsFCM, IF, IHC-p
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
SpeciesRabbit
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ClonalityMonoclonal

Specifications/Features

Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant

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