Rabbit Anti-CD21 Antibody MBS4380814 from MyBioSource.com

Product Specs
ItemRabbit Anti-CD21 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380814
ReactivityHuman
Format200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Paraffin
SpeciesRabbit
Molecular Weight140kDa
TargetCD21
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
NCBI Gene AliasesC3DR, CR, CD21, SLEB9, CVID7
Conjugate/TagUnconjugated
IsotypeIgG
CloneCR2/3124R
NCBI Full Gene Namecomplement C3d receptor 2
ClonalityMonoclonal
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)

Specifications/Features

Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation

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