MyBioSource.com's RUNX2 antibody - middle region is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This is a rabbit polyclonal antibody against RUNX2. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)