MyBioSource.com's Anti-GATA1 Rabbit Monoclonal Antibody is a Rabbit monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Precipitation, ChIP, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed: 24245781)