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Antibodies
Anti-CDKN2A/p19ARF antibody
Anti-CDKN2A/p19ARF antibody from Abcam
(1)
Write a review
Citations:
(160)
Supplier Page
Supplier Page from
Abcam for
Anti-CDKN2A/p19ARF antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-CDKN2A/p19ARF antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab80
Antibody Type
Primary
Clonality
Polyclonal
Host
Rabbit
Quantity
100 UG
Applications
ELISA, Immunocytochemistry, Western blot
Isotype
IgG
Conjugate/Tag
Unconjugated
Format
The serum has been purified on a peptide-NHS-activated Sepharose column. Specific antibodies have been eluted with 100 mM glycine pH 2.5. The purified antibodies have been dialysed against PBS pH 7.4
Concentration
1 mg/ml
Research Area
Epigenetics
Gene Name
CDKN2A
Reactivity
Mouse
Target
CDKN2A/p19ARF
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (160)
(1)
IFNγ Transcribed by IRF1 in CD4+ Effector Memory T Cells Promotes Senescence-Associated Pulmonary Fibrosis
Aging and disease
December 1, 2023
Chen H, Wang Q, Li J, Li Y, Chen A, Zhou J, Zhao J, Mao Z, Zhou Z, Zhang J,
et al
.
experiments.
Western blots
Western blots
were generated as previously described. Primary antibodies against
p19
(
ab80
,
Abcam
, USA), p21 (
sc-471
,
Santa Cruz Biotechnology Inc
., USA),
p16
(
ab211542
, Abcam, USA),
p53
(
sc-126
,
(2)
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression
bioRxiv
July 20, 2023
Naveen Kumar Tangudu, Raquel Buj, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Maureen A. Lyons, Uma R. Chandran, Katherine M. Aird
Rabbit anti-p16
INK4A
(
Cell Signaling Technology
,
29271
;
1:1000
); Rabbit anti-CDKN2A/
p19 ARF
(
Abcam
,
ab80
;
1:1000
);
mouse
anti-β-actin (
Sigma Aldrich
,
A1978
;
1:10000
). Secondary antibodies:
Anti-mouse IgG, HRP-linked
(3)
ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
Nature communications
March 3, 2023
Mainwaring OJ, Weishaupt H, Zhao M, Rosén G, Borgenvik A, Breinschmid L, Verbaan AD, Richardson S, Thompson D, Clifford SC,
et al
.
Cleaved Caspase-3 [Asp175] (
Abcam
, Cat #
ab49899
(WB
1:500
,
IHC
1:1500
)),
CDKN2A
/
p19ARF
(
Abcam
, Cat #
ab80
(
1:1000
)), cMYC [Y69] (
Abcam
, Cat #
ab32072
(WB
1:1000
,
IHC
1:500
)), Cyclophilin B (
Cell Signalling
(4)
Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes
Journal of Inflammation Research
August 16, 2022
Yingze Li, Guojian Fang, Wei Cao, Jiali Yuan, Shuai Song, Hong Peng, Yuepeng Wang, Qunshan Wang
(
Abcam
,
ab137332
), MMP8 (
Abcam
,
ab53017
), MMP13 (
Abcam
,
ab39012
),
p16
(Abcam,
ab211542
),
p19
(
Abcam
,
ab80
),
p21
(Abcam,
ab188224
), collagen-I (
Abcam
,
ab254113
), collagen-III (Servicebio, GB111323), or GAPDH
(5)
Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis
PLoS pathogens
June 1, 2022
Palrasu M, Zaika E, Paulrasu K, Caspa Gokulan R, Suarez G, Que J, El-Rifai W, Peek RM Jr, Garcia-Buitrago M, Zaika AI.
normal mouse IgG
(
sc-2025
) from
Santa Cruz Biotechnology
(Santa Cruz, CA);
p14ARF
(
ab185620
) and
p19ARF
(
ab80
) from
Abcam
(Cambridge, MA);
ULF
/
TRIP12
(
A301-814A
) and
MKRN1
(
A300-990A
) from
Bethyl Laboratories
(Montgomery,
(6)
N
-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese Mice
Metabolites
April 14, 2022
Khanh Hoang N, Maegawa E, Murakami S, Schaffer SW, Ito T.
Germany). For detection of Laminin, the
frozen section
was immunostained by using anti-laminin antibody (
ab80
,
Abcam
, Cambridge, UK;
1:100
) and Alexa Fluor 488-conjugated second antibody (Life Technologies;
1:400
)
(7)
A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target
Laboratory Investigation
April 1, 2022
Natasja Franceschini, Raffaele Gaeta, Paul Krimpenfort, Inge Briaire-de Bruijn, Alwine B. Kruisselbrink, Karoly Szuhai, Ieva Palubeckaitė, Anne-Marie Cleton-Jansen, Judith V. M. G. Bovée
UK), p16 (
1:1000
,
clone
JC8, Immunologic, WellMed BV, Duiven, The Netherlands), p19 (
1:5000
,
clone
ab80
,
Abcam
), Rb (
1:500
,
clone
G3-245, BD Pharmingen, San Diego, CA, USA), Histon H3 (
1:1000
, Cell Signalling,
(8)
A Series of BRAF- and NRAS-Driven Murine Melanoma Cell Lines with Inducible Gene Modulation Capabilities
JID Innov
March 1, 2022
Bok I, Angarita A, Douglass SM, Weeraratna AT, Karreth FA.
United Kingdom),
p16INK4a
(
1:2,000
, catalog number
ab211542
;
Abcam
),
p19ARF
(
1:1,000
, catalog number
ab80
;
Abcam
), p53 (
1:1,000
, catalog number
3036-100
;
BioVision
, Milpitas, CA), phosphorylated
AKT
S473 (
1:2,000
,
(9)
Age-related GSK3β overexpression drives podocyte senescence and glomerular aging
Journal of Clinical Investigation
February 15, 2022
Yudong Fang, Bohan Chen, Zhangsuo Liu, Athena Y. Gong, William T. Gunning, Yan Ge, Deepak Malhotra, Amira F. Gohara, Lance D. Dworkin, Rujun Gong
anti-fibronectin (
sc-9068
,
Santa Cruz Biotechnology
); rabbit anti-fibronectin (
ab2413
,
Abcam
); rabbit anti-p19 (
ab80
,
Abcam
); rabbit anti-CDK2 (
ab32147
,
Abcam
); rabbit anti-CDK4 (
ab199728
,
Abcam
); rabbit anti–phosphorylated
(10)
Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria
Aging (Albany NY)
January 15, 2022
Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-Myers
Tween for 1 h at RT and stained with the following primary antibodies: rabbit anti-CDKN2A/p19ARF
1:100
(
ab80
,
Abcam
), rabbit anti-PECAM-1/CD31
1:30
(LB-B4737, LifeSpan BioScience) and
rat anti-CD3
1:400
(
MCA1477
,
(11)
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin
Oxidative medicine and cellular longevity
January 1, 2022
Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L,
et al
.
30 μg protein was used for analysis. Primary antibodies against
p16
(
ab211542
),
p16
(
ab152099
),
p19
(
ab80
),
tumor
necrosis
factor-α (TNF-α) (
ab183218
), IL-1β (
ab9722
),
NLRP3
(
ab263899
),
ApoE
(
ab183597
),
NLRC4
(12)
Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication
npj Precision Oncology
December 1, 2021
Yueshuo Li et al.
USA). Primary antibodies include anti-p18 INK4C (
1:1000
, Cat: ab192239), and anti-p19 (
1:1000
, Cat:
ab80
), p15 (
1:1000
, Cat:
ab53034
), p16 (
1:1000
, Cat: EPR20418),
p21
(
1:1000
, Cat:
ab109520
), p27 (
1:1000
,
(13)
Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration
PLoS genetics
December 1, 2021
Flora P, Li MY, Galbo PM Jr, Astorkia M, Zheng D, Ezhkova E.
Cat#
649601
), Rabbit anti-
LEF1
(
1:100
,
Cell Signaling
, Cat#
2230S
), Rabbit anti-P19 (ARF) (
1:200
,
Abcam
, Cat#
ab80
), Goat anti-
EDAR
(
1:100
,
R&D Systems
, Cat#
AF745
) and
Sheep
anti-
FOXC2
(
1:100
,
R&D Systems
, Cat#
AF6989
).
(14)
Intramuscular injection of Botox causes tendon atrophy by induction of senescence of tendon-derived stem cells
Stem Cell Research & Therapy
December 1, 2021
Peilin Chen et al.
primary antibodies used
for Western Blotting
were purchased from either
Abcam
® (
anti-CDKN2A/p19ARF
ab80
,
anti-p16 ARC
ab51243
,
anti-Tenomodulin
ab2023276 and anti-MMP13
ab39012
, anti-MMP9
ab38898
, anti-beta
(15)
Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells
Science advances
August 1, 2021
Pessoa Rodrigues C, Akhtar A.
#
A2066
), H3 (
1:5000
;
Active Motif
, #
39763
), p16INKA (
1:1000
;
Abcam
, #
ab54210
), p19INKD (
1:1000
;
Abcam
, #
ab80
), and H4K16ac (
1:2000
; Millipore, #07-32) diluted in PBS–5% BSA. The
membrane
was then incubated with
(16)
The Common Germline
TP53-R337H
Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model
Cancer Research
May 1, 2021
John R. Jeffers et al.
were detected
by Western blot
analysis using the following primary antibodies:
p53
(1C12); p19Arf (
ab80
;
ABCAM
).
(17)
Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence
Cell Cycle
January 2, 2021
Wesam Bazzar, Matteo Bocci, Eduar Hejll, Vedrana Högqvist Tabor, Per Hydbring, Alf Grandien, Mohammad Alzrigat, Lars-Gunnar Larsson
developed with chemiluminescent HRP substrate. Antibodies used
for immunoblotting
were anti-p19ARF (
ab80
,
Abcam
), anti-p21CIP1 (
sc-397
,
Santa Cruz
), anti-Rb (
558385
,
BD
Pharmingen), cyclin A1 (
sc-239
,
Santa Cruz
(18)
p19Arf Exacerbates Cigarette Smoke-Induced Pulmonary Dysfunction
Biomolecules
March 17, 2020
Ryuta Mikawa, Tadashi Sato, Yohei Suzuki, Hario Baskoro, Koichiro Kawaguchi, Masataka Sugimoto
The section were immunostained with rabbit polyclonal antibody against
p19Arf
(
1:200
dilution, cat#
ab80
,
Abcam
, Cambridge, UK),
rat
monoclonal antibody against
p19Arf
(
1:100
dilution, cat#
sc-32748
,
Santa Cruz Biotechnology
(19)
Collaboration of MYC and RUNX2 in lymphoma simulates T‐cell receptor signaling and attenuates p53 pathway activity
Journal of Cellular Biochemistry
October 1, 2019
Jodie Hay, Kathryn Gilroy, Camille Huser, Anna Kilbey, Alma Mcdonald, Amanda MacCallum, Ailsa Holroyd, Ewan Cameron, James C. Neil
α‐p21WAF1, α‐actin (
sc‐1207
,
sc‐471
, and
sc‐1616
, respectively;
Santa Cruz Biotechnology
), α‐p19ARF (
ab80
;
Abcam
), α‐p53 and α‐SMYD2 (IC12 and D14H7, respectively; Cell Signaling Technology).
Western blots
(20)
ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation
Molecular neurobiology
August 1, 2019
Benkafadar N, François F, Affortit C, Casas F, Ceccato JC, Menardo J, Venail F, Malfroy-Camine B, Puel JL, Wang J.
(Thr180/Tyr182, 1/1000,
Cell Signaling
#
9211
), p16 (1/1000, BD
Pharmingen
#
551154
), p19 (1/1000,
Abcam
#
ab80
),
BubR1
(1/1000,
Abcam
#
ab183496
),
FOXO3a
(1/1000,
Cell Signaling
#
2497
), and nuclear factor erythroid
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Reviews
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(1)
3/14/2016
Great p19 Antibody
A M
Our lab works with a number of different cell cycle regulator proteins in the context of several different types of cancer. We purchased this antibody from Abcam on the recommendation of another lab, ...
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Anti-CDKN2A/p19ARF antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
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Company Info
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