Description
Product Characteristics: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.,RGS7,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Signal Transduction,G2/M DNA Damage Checkpoint,RGS7
Target Information: acts as a GTPase activating protein, regulates activation and deactivation kinetics of G-protein coupled inward rectifier K+ channel, binds Galphao, Galphai3, and Galphaz