MEKK3 (D36G5) Rabbit mAb 5727S from Cell Signaling Technology

Product Specs
ItemMEKK3 (D36G5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number5727S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetMEKK3
HostRabbit
NCBI Gene AliasesMAPKKK3, MEKK3
ClonalityMonoclonal
NCBI Full Gene Namemitogen-activated protein kinase kinase kinase 3
Research AreaMAP Kinase Signaling
IsotypeIgG
CloneD36G5
Molecular Weight78

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Elemene as a binding stabilizer of microRNA-145-5p suppresses the growth of non-small cell lung cancerJournal of Pharmaceutical AnalysisOctober 2, 2024Meirong Zhou, Jiayue Wang, Yulin Peng, Xiangge Tian, Wen Zhang, Junlin Chen, Yue Wang, Yu Wang, Youjian Yang, Yongwei Zhang, et al.(8242; Cell Signaling Technology), cyclooxygenase-2 (COX-2) (12,282; Cell Signaling Technology), MAK3P3 (5727; Cell Signaling Technology), IκBα (4812; Cell Signaling Technology), phospho-IκBα (Ser32) (2859; Cell Signaling Technology

(2) TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal developmentiScienceAugust 18, 2023Erdyni N. Tsitsikov, Khanh P. Phan, Yufeng Liu, Alla V. Tsytsykova, Mike Kinter, Lauren Selland, Lori Garman, Courtney Griffin, Ian F. Dunnwith Blotting-Grade Blocker (BIO-RAD, 1706404); and probed with antibodies from CellSignaling: MEKK3 (5727), MEKK2 (5727), MARK2 (9118), ERK5 (3552), MEK5 (40737), and SCRIB (4475). Sp1 antibody (Sigma Aldrich,

(3) Simplex cerebral cavernous malformations with MAP3K3 mutation have distinct clinical characteristicsFrontiers in NeurologyAugust 26, 2022Ran Huo et al.were incubated with the following primary antibodies: CCM2 (1:1000; 123930; Abcam), MEKK3 (1:1000; #5727; CST), TM (1:1000; 109189; Abcam), phospho-NF-κB (1:1000; #3033; CST), ZO-1 (1:750; #13663; CST), Occludin

(4) miR‐181b regulates vascular endothelial aging by modulating an MAP3K3 signaling pathwayThe FASEB JournalJune 1, 2022Haoyang Zhou, Dafeng Yang, Henry S. Cheng, Michael G. McCoy, Daniel Pérez‐Cremades, Stefan Haemmig, Danny Wong, Lei Chen, Mark W. FeinbergBcl-2 (1:1000, 3498, Cell Signaling), cleaved caspase-3 (1:1000, 9661, Cell Signaling), MEKK3 (1:1000, 5727, Cell Signaling), p16 (1:1000, ab51243, Abcam), p21(1:1000, ab109520, Abcam), p-γH2AX (1:1000, 9718,

(5) Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cellsMolecular therapy. Nucleic acidsSeptember 3, 2021Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J.p-ERK1/2 (Thr202/Tyr204) (#4370), ERK1/2 (#4695), AKT (#9272), p-AKT (Ser473) (#4060), and MAP3K3 (#5727) were purchased from Cell Signaling Technology (Danvers, MA, USA); anti-MAP3K2 was from Proteintech

(6) MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesisPLoS biologyDecember 1, 2018Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, et al.using antigen VGQGGNQPKAGPLRAGTC, Phospho-WDR62 1053T (present from Dominic) [52], and MEKK3 (CST, 5727, 1:1,000). The antibodies used for immunostaining were Sox2 (abcam, ab97959, 1:1,000), Pax6 (Covance,

(7) A Mechano-Activated Cell Reporter System as a Proxy for Flow-Dependent Endothelial AtheroprotectionSLAS discovery : advancing life sciences R & DSeptember 1, 2018Slegtenhorst BR, Fajardo Ramirez OR, Zhang Y, Dhanerawala Z, Tullius SG, García-Cardeña G.Holm– Sidak multiple comparison test (lower panel). primary antibody rabbit anti-MEKK3 diluted 1:1000 (5727S, Cell Signaling, Danvers, MA) and rabbit anti-GAPDH 1:3000 (sc-25778, Santa Cruz Biotechnologies, Dallas,

(8) MEKK3 Sustains EMT and Stemness in Pancreatic Cancer by Regulating YAP and TAZ Transcriptional ActivityAnticancer researchApril 1, 2018Santoro R, Zanotto M, Carbone C, Piro G, Tortora G, Melisi D.antirabbit (sc-2030) antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). MEKK3 (#5727, 1:1,000), AXL (#3269, 1:1000), p65 (#4764, 1:1,000), p-p65 (#3031, 1:1,000) were purchased by Cell Signaling

(9) Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in MacrophagesThe Journal of ImmunologyNovember 15, 2017Fansheng Kong, Zhiwei Liu, Viral G. Jain, Kenjiro Shima, Takuji Suzuki, Louis J. Muglia, Daniel T. Starczynowski, Chandrashekhar Pasare, Sandip Bhattacharyya(4504), anti–K63-linked polyubiquitin Ab (5621), anti-MEK1/2 (8727), anti-AIF (5318), anti-PDI (3501), anti-MEKK3 (5727), b-TrCP (4394), normal rabbit IgG control (2729) (Cell Signaling Technology, Beverly, MA); anti-TAK1 (7162),

(10) Collagen Sponge Functionalized with Chimeric Anti-BMP-2 Monoclonal Antibody Mediates Repair of Critical-Size Mandibular Continuity Defects in a Nonhuman Primate ModelBioMed Research InternationalMarch 16, 2017Yilin Xie, Yingying Su, Seiko Min, Jianxia Tang, Bee Tin Goh, Leonardo Saigo, Sahar Ansari, Alireza Moshaverinia, Chunmei Zhang, Jinsong Wang, et al.of divergent growth factor effects in mesenchymal stem cell differentiation,” Science, vol. 308, no. 5727, pp. 1472–1477, 2005. [7] J. Czyz and A. M. Wobus, “Embryonic stem cell differentiation: the role of

(11) KLF 4 is a key determinant in the development and progression of cerebral cavernous malformationsEMBO Molecular MedicineJanuary 1, 2016Roberto Cuttano et al.rabbit (07‐039, Upstate); VE‐PTP rabbit (produced and purified by New England Peptide); MEKK3 rabbit (5727, Cell Signaling); MEK5 mouse (610957, BD); BMP6 sheep (LS‐C150156, LS‐BIO); GAPDH mouse (SC‐32233, Santa Cruz

(12) IQGAP Family Members in Yeast, Dictyostelium, and Mammalian CellsInternational journal of cell biologyJanuary 1, 2012Katie B Shannonof divergent growth factor eﬀects in mesenchymal stem cell diﬀerentiation,” Science, vol. 308, no. 5727, pp. 1472–1477, 2005. [68] A. Heil, A. R. Nazmi, M. Koltzscher et al., "S100P is a novel interaction

(13) Proteomic Definitions of Mesenchymal Stem CellsStem Cells InternationalMarch 3, 2011Martin H. Maurerof divergent growth factor eﬀects in mesenchymal stem cell diﬀerentiation,” Science, vol. 308, no. 5727, pp. 1472–1477, 2005. [44] P. J. Mishra, P. J. Mishra, J. W. Glod, and D. Banerjee, “Mesenchymal stem cells

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MEKK3 (D36G5) Rabbit mAb

MEKK3 (D36G5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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MEKK3 (D36G5) Rabbit mAb from Cell Signaling Technology

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