Human Type I Interferon Neutralizing Antibody Mixture 39000-1 from PBL Assay Science

Product Specs
ItemHuman Type I Interferon Neutralizing Antibody Mixture
CompanyPBL Assay Science
Price $645.00Supplier Page View Company Product Page
Catalog Number39000-1
Quantity0.2 ml
ApplicationsNeutralization
Conjugate/TagUnconjugated
ReactivityHuman

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PBL Assay Science

131 Ethel Road West. Suite 6

Piscataway, New Jersey

United States

Phone: 1-877-725-8881
1-732-777-9123
1-732-777-9141

Company Profile

Website: www.pblassaysci.com

(1) Interferon-β induction heterogeneity during KSHV infection is correlated to levels and activation of the transcription factors ATF2 and RelA, and not IRF3PLOS PathogensFebruary 11, 2026Machika Kaku, Marta Maria GagliaS777525MG), a mixture of neutralizing antibodies against type I IFNs at 1:2000 dilution (PBL Assay Science 39000–1), 10 μM TBK1 inhibitor (MRT67307; Medchemexpress LLC HY130185MG), 10 μM cGAS inhibitor (G140; Invivogen

(2) Genetic ancestry shapes dengue virus infection in human skin explantsProceedings of the National Academy of Sciences of the United States of AmericaJuly 15, 2025Castanha PMS, Martí MM, Duangkhae P, Taddonio JM, Cooper KL, Wallace M, Kettenburg G, Erdos G, Chavva H, Alex A, et al.(R&D Systems, 201-LB-005-CF), 20 μg of neutralizing antibody to human type 1 IFN (PBL Assay Science, 39000-1), 30 ng of neutralizing antibody to human IL-1β (R&D Systems, MAB601-25), 30 ng isotype control antibody

(3) Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancerMolecular Therapy: OncologySeptember 19, 2024Karen Geoffroy, Victor Mullins-Dansereau, Kim Leclerc-Desaulniers, Mélissa Viens, Marie-Claude Bourgeois-Daigneault(11410-2, PBL assay science, Piscataway, NJ) or a mixture of human type I IFN neutralizing antibodies (39000-1, PBL assay science) were also used at the indicated concentrations for some experiments. In all cases,

(4) Interferons prime the endothelium for toll-like receptor–mediated thrombin generationJournal of Thrombosis and HaemostasisApril 1, 2024Kelsey D. Sack, Nathan Eaton, Maneli Doroudian Tehrani, Robert Flaumenhaftanti-type I IFN antibodies (including antibodies to IFNα, IFNβ, IFNω, IFNκ, IFNε; PBL Assay Science, 39000–1) or Type II IFN antibody (anti-IFNγ, PBL Assay Science, 31500–1) for 3 hours, and incubated on ECs for

(5) Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi's Sarcoma-Associated Herpesvirus InfectionmBioDecember 20, 2022Tabtieng T, Lent RC, Kaku M, Monago Sanchez A, Gaglia MM.dilutions of a mixture of neutralizing antibodies against type I IFNs (PBL Assay Science, catalog number 39000-1). The concentrations of all drug treatments were chosen based on common concentrations used in previously

(6) Sequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tractEmerging microbes & infectionsDecember 1, 2022Essaidi-Laziosi M, Alvarez C, Puhach O, Sattonnet-Roche P, Torriani G, Tapparel C, Kaiser L, Eckerle I.similar dual assays were repeated where a mixture of anti-type I neutralizing antibodies diluted 1/50 (39000-1, PBL Assay ScienceTM, Piscataway, NJ, USA) and 10μg/mL of anti-IFN-λ1 (MAB15981-100, RandD, Minneapolis,

(7) Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responsesScience advancesFebruary 25, 2022Nguyen LC, Yang D, Nicolaescu V, Best TJ, Gula H, Saxena D, Gabbard JD, Chen SN, Ohtsuki T, Friesen JB, et al.μg/ml) (MAB285-100), and 1:25 dilution of Human Type I IFN Neutralizing Ab Mixture (PBL Assay Science, 39000-1) 2 hours before infection. Cells were then infected with 0.5 MOI and incubated for 24 hours, after which

(8) SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory responseNat AgingFebruary 1, 2022Tsuji S, Minami S, Hashimoto R, Konishi Y, Suzuki T, Kondo T, Sasai M, Torii S, Ono C, Shichinohe S, et al.inhibitor tocilizumab (Selleck, A2012; 50 μg ml−1), type I IFN neutralization antibody (PBL Assay Science, 39000-1; 1:200) and the p38 MAP kinase inhibitor SB203580 (Selleck, S1076; 10 μM) were administrated at the

(9) Human plasmacytoid dendritic cells mount a distinct antiviral response to virus-infected cellsScience ImmunologyApril 2, 2021Tae Jin Yun et al.ICAM-3 (clone: CBR-IC3/1, eBioscience), CD62 E/P-selectin (clone: BBIG-E6 (13D5), R&D) and IFN-I/IFNAR2 (39000-1, PBL) for 30 minutes, or with 3 μM single-stranded oligodeoxynucleotides ODN 20958 (TLR7 antagonist,

(10) Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytesMolecular Biology ReportsJanuary 1, 2021Tatsuro Saruga, Tadaatsu Imaizumi, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Eiji Sasaki, Norihiro Sasaki, Ryoko Uesato, Yasuyuki Ishibashiwas obtained from BIOWEST (Nuaille, France). Human type I interferon neutralizing antibody mixture (39000-1) was purchased from PBL Assay Science (Piscataway, NJ, USA). Small interfering RNA (siRNA) against MDA5

(11) Interferon-Dependent and Respiratory Virus-Specific Interference in Dual Infections of Airway EpitheliaScientific reportsJune 24, 2020Essaidi-Laziosi M, Geiser J, Huang S, Constant S, Kaiser L, Tapparel C.MAB15981-100; R&D Systems, Minneapolis, MN, USA) and a mixture of anti-type I IFN-neutralizing antibodies (39000-1, PBL Assay Science) diluted 1/50 in the basal sample during the pretreatment. Virus RNA load quantification.

(12) Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and diseaseNature communicationsOctober 17, 2019Szabo PA, Levitin HM, Miron M, Snyder ME, Senda T, Yuan J, Cheng YL, Bush EC, Dogra P, Thapa P, et al.cells were pre-incubated with Human Type 1 IFN Neutralizing Antibody Mixture (PBL Assay Science, Cat# 39000-1) according to manufacturer’s instructions, or 1 µg/mL of both anti-IFNγ (R&D Systems, MAB285, clone

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Human Type I Interferon Neutralizing Antibody Mixture from PBL Assay Science

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Human Type I Interferon Neutralizing Antibody Mixture from PBL Assay Science

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