CD4 Antibody Alexa Fluor 488 53-0049-42 from Thermo Fisher Scientific

Product Specs
ItemCD4 Antibody Alexa Fluor 488
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number53-0049-42
Quantity100 Tests
ApplicationsFlow Cytometry
Concentration5 µL/Test
Conjugate/TagAlexa Fluor™ 488
FormatPBS with BSA and 0.09% sodium azide; pH 7.2
PurityAffinity chromatography
ReactivityHuman
TargetCD4
IsotypeIgG1 kappa
CloneRPA-T4
HostMouse
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
Storage4°C, store in dark, DO NOT FREEZE!

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) A Potent Single-Domain Antibody Targeting LAG-3 for Efficient Tumor ImmunotherapyCurr Issues Mol BiolMay 4, 2026Mengfei Dong, Wenjie Li, Tailin Wang, Ming Li, Jingyi Zhang, Xianglei Liu(Sino biological, Beijing, China, Cat: 10086-MM05-A), anti-CD4-488 (Thermo Fisher, Waltham, MA, USA, Cat: 53-0049-42), and anti-CD8-PE (Sino biological, Beijing, China, Cat: 10980-MM48-P) antibodies for 30 min on ice

(2) IL-4 activates ULK1/Atg9a/Rab9 in asthma, NLRP3 inflammasomes, and Golgi fragmentation by increasing autophagy flux and mitochondrial oxidative stressRedox biologyMay 1, 2024Xu C, Song Y, Liu W, Liu R, Bai Q, Li L, Wang C, Yan G.

(3) Myeloid‑derived suppressor cell accumulation induces Treg expansion and modulates lung malignancy progressionBiomedical reportsApril 1, 2024Wan Y, Mu X, Zhao J, Li L, Xu W, Zhang M.

(4) Paediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunctionBritish journal of pharmacologyApril 1, 2024Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, et al.

(5) HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in miceNature communicationsMarch 13, 2024Long J, Chen X, He M, Ou S, Zhao Y, Yan Q, Ma M, Chen J, Qin X, Zhou X, et al.

(6) miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPKExperimental biology and medicine (Maywood, N.J.)January 1, 2024Dai Q, Shi R, Zhang G, Wang Y, Ye L, Peng L, Guo S, He J, Yang H, Jiang Y.

(7) Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic ratsJournal of biochemical and molecular toxicologySeptember 1, 2023Peng H, Lv Y, Li C, Cheng Z, He S, Wang C, Liu J.

(8) Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytesJCI insightFebruary 8, 2023Zhang M, Chong KK, Chen ZY, Guo H, Liu YF, Kang YY, Li YJ, Shi TT, Lai KK, He MQ, et al.

(9) Dynamics of humoral and cellular response to three doses of anti-SARS-CoV-2 BNT162b2 vaccine in patients with hematological malignancies and older subjectsFrontiers in immunologyJanuary 1, 2023Laquintana V, Mottini C, Marchesi F, Marcozzi B, Terrenato I, Sperandio E, de Latouliere L, Carrieri F, Pimpinelli F, Pontone M, et al.

(10) Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunityNature communicationsDecember 10, 2022McEvoy CM, Murphy JM, Zhang L, Clotet-Freixas S, Mathews JA, An J, Karimzadeh M, Pouyabahar D, Su S, Zaslaver O, et al.

(11) Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 ReceptorCellsAugust 19, 2022Rode AKO, Buus TB, Mraz V, Al-Jaberi FAH, Lopez DV, Ford SL, Hennen S, Eliasen IP, Klewe IV, Gharehdaghi L, et al.

(12) Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seqCell discoveryMay 10, 2022Wang B, Wang C, Wan Y, Gao J, Ma Y, Zhang Y, Tong J, Zhang Y, Liu J, Chang L, et al.

(13) Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenariansFrontiers in immunologyJanuary 1, 2022Zhong J, Ding R, Jiang H, Li L, Wan J, Feng X, Chen M, Peng L, Li X, Lin J, et al.

(14) Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cellsMolecular therapy. Methods & clinical developmentSeptember 10, 2021Kierkels GJJ, van Diest E, Hernández-López P, Scheper W, de Bruin ACM, Frijlink E, Aarts-Riemens T, van Dooremalen SFJ, Beringer DX, Oostvogels R, et al.

(15) Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell ActivationCancersApril 13, 2021Prat M, Salon M, Allain T, Dubreuil O, Noël G, Preisser L, Jean B, Cassard L, Lemée F, Tabah-Fish I, et al.

(16) Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 CellsBiomolecules & therapeuticsMarch 1, 2021Yoon H, Sung JH, Song MJ.

(17) Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF InhibitionFrontiers in immunologyJanuary 1, 2021Yeku OO, Rao TD, Laster I, Kononenko A, Purdon TJ, Wang P, Cui Z, Liu H, Brentjens RJ, Spriggs D.

(18) Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic painThe Journal of international medical researchJuly 1, 2020He J, Xu Y, Yi M, Gu C, Zhu Y, Hu G.

(19) HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune MicroenvironmentJournal of CancerJanuary 1, 2020Kim YD, Park SM, Ha HC, Lee AR, Won H, Cha H, Cho S, Cho JM.

(20) Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cellsJournal of biological methodsJanuary 1, 2020Manuszak C, Brainard M, Thrash E, Hodi FS, Severgnini M.

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CD4 Antibody Alexa Fluor 488

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CD4 Antibody Alexa Fluor 488 from Thermo Fisher Scientific

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CD4 Antibody Alexa Fluor 488 from Thermo Fisher Scientific

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