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Antibodies
Anti-DDIT3 antibody [9C8]
Anti-DDIT3 antibody [9C8] from Abcam
(2)
Write a review
Citations:
(189)
Supplier Page
Supplier Page from
Abcam for
Anti-DDIT3 antibody [9C8]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-DDIT3 antibody [9C8]
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab11419
Antibody Type
Primary
Clonality
Monoclonal
Clone
9C8
Host
Mouse, Nude mouse
Quantity
10 UG, 100 UG
Applications
Immunocytochemistry/ Immunofluorescence, Western blot, Immunocytochemistry/ Immunofluorescence, Western blot
Isotype
IgG2b
Conjugate/Tag
Unconjugated
Concentration
1 mg/ml
Research Area
Epigenetics
Gene Name
DDIT3
Reactivity
Human, Mouse
Target
DDIT3
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (189)
(1)
Tanshinone IIA attenuates valvular interstitial cells’ calcification induced by oxidized low density lipoprotein via reducing endoplasmic reticulum stress
Open Med (Wars)
September 25, 2023
Fang Chen, Dongqiang Yang, Yuhua Ru, Yu Bai, Xueliang Pei, Jie Sun, Shan Cao, Weiguang Wang, Aishe Gao
Santa Cruz Biotechnology, Inc. (Santa Cruz, CA) except
GRP78
, CHOP, and XBP1s (
Abcam
; Cat.
ab212054
,
ab11419
,
ab241571
). Porcine VICs were dissolved in commercial radio
immunoprecipitation assay
lysis buffer (Beyotime,
(2)
Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors
Signal Transduction and Targeted Therapy
September 25, 2023
Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao,
et al.
p-
JNK
(
1: 1000
,
4668
, Cell Signaling Technology), Caspase 12 (
1: 2000
,
ab62484
,
Abcam
), CHOP (
1: 1000
,
ab11419
,
Abcam
),
PERK
(
1: 1000
,
5683
,
Cell Signaling Technology
), p-PERK (
1: 1000
,
3179
,
Cell Signaling Technology
),
(3)
Zinc oxide nanoparticles inhibit malignant progression and chemotherapy resistance of ovarian cancer cells by activating endoplasmic reticulum stress and promoting autophagy
Experimental and Therapeutic Medicine
September 14, 2023
Wenli Gu, Caihong Yang
factor 4 (ATF4;
1:1,000
; cat. no. ab270980; Abcam), C/EBP homologous protein (CHOP;
1:1,000
; cat. no.
ab11419
;
Abcam
), Caspase 12 (
1:1,000
; cat. no.
ab62484
;
Abcam
), LC3 (
1:1,000
; cat. no.
ab192890
;
Abcam
),
Beclin1
(4)
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC
Science Advances
September 13, 2023
Ebru Boslem, Saskia Reibe, Rodrigo Carlessi, Benoit Smeuninx, Surafel Tegegne, Casey L. Egan, Emma McLennan, Lauren V. Terry, Max Nobis, Andre Mu,
et al.
against p-
JNK
(
9251
,
Cell Signaling Technology
), total
JNK
(
9252
,
Cell Signaling Technology
), CHOP/ddit3 (
ab11419
,
Abcam
), calnexin (
2679
,
Cell Signaling Technology
), heat
HSF1
(
4356
,
Cell Signaling Technology
), phospho-eif2α
(5)
GRP78 inhibitor HA15 increases the effect of Bortezomib on eradicating multiple myeloma cells through triggering endoplasmic reticulum stress
Heliyon
September 2, 2023
Yirong Chen, Yuchen Tao, Kexin Hu, Jiahui Lu
(
1:1500
,
ab182858
,
Abcam
), GRP78 (
1:1000
,
ab21685
,
Abcam
),
ATF4
(
1:1000
,
ab216839
,
Abcam
), CHOP (
1:1000
,
ab11419
,
Abcam
), XBP1 (
1:1500
,
ab37152
,
Abcam
), and β-actin (
1:300
,
ab8226
,
Abcam
) for 1 h at room temperature.
(6)
Esophageal cancer stem cells reduce hypoxia-induced apoptosis by inhibiting the GRP78-perk-eIF2α-ATF4-CHOP pathway in vitro
Journal of Gastrointestinal Oncology
August 31, 2023
Ruijiang Lin, Minjie Ma, Biao Han, Ya Zheng, Yuping Wang, Yongning Zhou
rabbit anti-Caspase 12 polyclonal antibody (
ab62484
;
Abcam
); rabbit anti-CHOP monoclonal antibody (
ab11419
;
Abcam
); rabbit anti-GRP78 monoclonal antibody (
ab108615
;
Abcam
); rabbit anti-JNK monoclonal antibody
(7)
Characterization of circSEC11A as a novel regulator of Iodine-125 radioactive seed-induced anticancer effects in hepatocellular carcinoma via targeting ZHX2/GADD34 axis
Cell Death Discov
August 10, 2023
Dong Li, Wujie Wang, Bin Liu, Die Jin, Yang Wang, Guanghui He, Lei Guo, Wen Liu, Yuliang Li
including
ZHX2
(
ab205532
), GADD34 (
ab9869
), eIF2α (
ab169528
), p-eIF2α (32157),
ATF4
(
ab184909
), and CHOP (
ab11419
), were purchased form
Abcam
(Cambridge, UK). The secondary antibodies were purchased from ABclonal (Wuhan,
(8)
Houttuynia cordata Thunb. Hexane fraction induces MDA-MB-231 cell apoptosis via caspases, ER stress, cell cycle arrest and attenuated Akt/ERK signaling
Heliyon
July 28, 2023
Pitsinee Inthi, Hataichanok Pandith, Prachya Kongtawelert, Subhawat Subhawa, Ratana Banjerdpongchai
(ab227443), Akt (ab32505), pAkt (Ser473) (ab81283), ERK (ab196883), pERK (ab76299), GRP78 (ab21685), DDIT3 (
ab11419
), β-actin (
ab8227
) and peroxidase-labeled secondary antibodies: goat anti-rabbit IgG (
ab97051
) and goat
(9)
Schlafen4+-MDSC in Helicobacter-induced gastric metaplasia reveals role for GTPases
Frontiers in Immunology
June 2, 2023
Lin Ding, Sulaiman Sheriff, Ricky A. Sontz, Juanita L. Merchant
primary antibodies to SLFN4 peptides (custom made by GenScript), NOS2 (Abcam, #ab283655), CHOP (
Abcam
, #
ab11419
), cleaved
Caspase-3
(
Cell Signaling
, #
9661
), β-Tubulin (
Cell signaling
, #
5346S
),
GAPDH
(
MA5-15738
,
ThermoFisher
). Nucleotide
(10)
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response
Redox biology
April 1, 2023
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X.
24164-1-AP
), p-
JNK
(
1:1500
;
Proteintech
,
80024-1-RR
),
XBP1
(
1:1000
;
Abcam
,
ab220783
), CHOP (
1:1000
;
Abcam
,
ab11419
),
ATF6
(
1:1000
;
Proteintech
,
24169-1-AP
), and
POMT2
(
1:1000
;
Invitrogen
,
PA5-51987
). HRP-conjugated
(11)
Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail Signaling
International Journal of Medical Sciences
March 21, 2023
Yiru Wu, Yu Bai, Yiduo Feng, Qidong Zhang, Zongli Diao, Wenhu Liu
(Col-I) (Cat No.
14695-1-AP
, Proteintech),
PERK
(
ab229912
;
Abcam
, USA),
ATF4
(
ab216839
,
Abcam
), CHOP (
ab11419
,
Abcam
), GSK-3β (
ab93926
,
Abcam
), p-GSK-3β-Ser9 (
ab131097
Abcam
), and p-GSK-3β-Tyr216 (Cat No.
29125-1-AP
,
(12)
Sex differences in islet stress responses support female β cell resilience
Molecular metabolism
March 1, 2023
Brownrigg GP, Xia YH, Chu CMJ, Wang S, Chao C, Zhang JA, Skovsø S, Panzhinskiy E, Hu X, Johnson JD,
et al
.
Cell Signalling
), phospho-IRE1α (
1:1000
, Cat. #
PA1-16927
,
Thermo Fisher Scientific
), CHOP (
1:1000
, #
ab11419
,
Abcam
), β-actin (
1:1000
,
NB600-501
,
Novus Biologicals
). The signals were detected by secondary HRP-conjugated
(13)
Ischemic Postconditioning Attenuates Myocardial Ischemia-Reperfusion-Induced Acute Lung Injury by Regulating Endoplasmic Reticulum Stress-Mediated Apoptosis
Brazilian Journal of Cardiovascular Surgery
February 10, 2023
Aimei Li, Siyu Chen, Jianjiang Wu, Jiaxin Li, Jiang Wang
incubated with anti-GRP78 (
1:500
,
Abcam
,
ab21685
), anti-C/EBP homologous protein (CHOP) (
1:200
,
Abcam
,
ab11419
), anti-caspase-12 (
1:500
,
Abcam
,
ab62484
) or anti-β-actin antibody (
1:800
, Shanghai Shenggong, d110001),
(14)
An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response
The Journal of biological chemistry
February 1, 2023
Amin PH, Carlson KR, Wek RC.
Thermo Fisher Scientific
Cat No
PA5-24224
), ATF4 (
1:1000
, In-house (34)), CHOP (DDIT3) (
1:500
,
Abcam
Cat No
ab11419
), total
eIF2
(
1:3000
,
CST
Cat No
5324S
), p-eIF2α (
1:500
,
Abcam
Cat No
ab32157
),
GADD34
(
1:2000
,
Proteintech
(15)
Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice
Redox biology
February 1, 2023
Wu D, Su S, Zha X, Wei Y, Yang G, Huang Q, Yang Y, Xia L, Fan S, Peng X.
immunolabelled overnight at 4 °C with primary antibodies against G6PD (
Abcam
,
ab993
), CHOP (
Abcam
,
ab11419
),
AGR2
(
Abcam
,
ab76473
), O-GlcNAC (
Abcam
,
ab2739
), glutathione (Virogen, 101-A),
GRP78
(
Cell Signaling
,
(16)
Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
BMC Cancer
December 30, 2022
Xiaohui Liu, Bo Wu, Hong Chen, Haimei Sun, Xiaoxia Guo, Tingyi Sun, Deshan Zhou, Shu Yang
monoclonal anti-IRE1α (
1:1000
,
CST
, #
3294
, RRID:AB_823545),
mouse
monoclonal anti-DDIT3/CHOP (
1:1000
,
Abcam
,
ab11419
, RRID:AB_298023) and rabbit polyclonal
anti-ABCC10
(
1:1000
,
Abcam
,
ab107053
, RRID:AB_10864747).
Mouse
(17)
Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER Stress
Microbiology spectrum
December 21, 2022
Liu Z, Fu Y, Huang Y, Zeng F, Rao J, Xiao X, Sun X, Jin H, Li J, Yang J,
et al
.
anti-PERK (
Abcam
,
ab65142
,
1:500
), anti-phosphate eIF2α (
Abcam
,
ab214434
,
1:1,000
), anti-CHOP (
Abcam
,
ab11419
,
1:2,000
), anti-Caspase 3 (
Abcam
,
ab208161
,
1:1,000
), anti-PARP1 (Invitrogen, 436400,
1:2,000
) and rabbit
(18)
Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain
International Journal of Molecular Sciences
December 6, 2022
Ryosuke Nomura, Nobumasa Takasugi, Hideki Hiraoka, Yuta Iijima, Takao Iwawaki, Yoshito Kumagai, Masatake Fujimura, Takashi Uehara
protein (GFP) (
1:200
; #M048-3, Medical & Biological Laboratories, Nagoya, Japan) and anti-CHOP (
1:1000
; #
ab11419
,
Abcam
, Cambridge, UK). Anti-HMG-CoA reductase degradation enzyme 1 (HRD1) (
1:500
; #
sc-130889
,
Santa Cruz Biotechnology
(19)
C/EBP homologous protein promotes Sonic Hedgehog secretion from type II alveolar epithelial cells and activates Hedgehog signaling pathway of fibroblast in pulmonary fibrosis
Respiratory Research
December 1, 2022
Xiaoyu Yang, Wei Sun, Xiaoyan Jing, Qian Zhang, Hui Huang, Zuojun Xu
rabbit
anti-prosurfactant protein C
antibody (
Abcam
,
ab90716
),
mouse
anti-CHOP (DDIT3) antibody (
Abcam
,
ab11419
), mouse anti-Sonic Hedgehog antibody (
Abcam
,
ab135240
), rabbit anti-Sonic Hedgehog (
Abcam
,
ab73958
),
(20)
Sevoflurane exposure causes neuronal apoptosis and cognitive dysfunction by inducing ER stress via activation of the inositol 1, 4, 5-trisphosphate receptor
Frontiers in Aging Neuroscience
October 20, 2022
Qi Zhang, Yanan Li, Xupeng Wang, Chunping Yin, Qi Zhou, Junfei Guo, Juan Zhao, Xiaohui Xian, Zhiyong Hou, Qiujun Wang
(ab264281), MFN1 (ab221661), MFN2 (ab260861),
GRP75
(
ab171089
), p-PERK (
ab192591
),
ATF4
(
ab184909
), CHOP (
ab11419
), cleaved caspase-3 (
ab32042
), cleaved
caspase-9
(
ab184786
), Bax (
ab32503
) and Bcl-2 (
ab32124
) were
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Reviews
Write a Review
(1)
2/9/2018
CHOP (DDIT3) Antibody
Andrea Estrada
This antibody was used to detect the presence of endoplasmic reticulum stress / unfolded protein response activation, specifically the IRE1 arm. This antibody used to validate gene expression of CHOP...
Read Review
(1)
4/12/2016
CHOP Protein Detection Via Western Blot
Claire Stewart
CHOP is a downstream marker of the unfolded protein response (UPR). Increased expression of CHOP indicates ER stress and activation of the UPR. Therefore, being able to quantitatively measure CHOP ...
Read Review
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Anti-DDIT3 antibody [9C8] from Abcam
Supplier Page
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Product Specs
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