Phospho-eIF2alpha (Ser51) (119A11) Rabbit mAb 3597L from Cell Signaling Technology

Product Specs
ItemPhospho-eIF2alpha (Ser51) (119A11) Rabbit mAb
CompanyCell Signaling Technology
Price $936.00 Inquire
Catalog Number3597L
Quantity300 µl
ApplicationsW, IP, IHC-P
ReactivityH, M, R, Mk, Dm
TargetEIF2S1/eIF2-alpha (Ser52) phosphate
Molecular Weight38
ModificationseIF2A (Ser52) phosphate
HostRabbit
NCBI Full Gene Nameeukaryotic translation initiation factor 2 subunit alpha
Clone119A11
NCBI Gene AliasesEIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
ClonalityMonoclonal
Research AreaTranslational Control

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) A stress-induced PI3P complex controls autophagy in erythroid precursorsiScienceApril 17, 2026Pooja Roy, Blake A. Rose, Suhita Ray, Venkatasai R. Dogiparthi, Meg A. Schaefer, Cheryl L. Stucky, Suyong Choi, Nicholas T. Woods, Kyle J. HewittRRID:AB_915794 "Anti-phospho-eIF2α (Ser51) (clone 119A11, rabbit monoclonal)",Cell Signaling Technology,Cat.: #3597; RRID:AB_390740 "Anti-eIF2α (clone L57A5, mouse monoclonal)",Cell Signaling Technology,Cat.: #2103;

(2) METTL3 stabilizes FASN mRNA by mediating m6A modification to promote malignant progression of diffuse large B-cell lymphomaCell & BioscienceMarch 18, 2026Xiangxiang Song, Yun Zhong, Nasha Yu, Wanwan Zou, Wuping Li, Qiaoli Lv, Qingfeng Luo, Xing Zhong,Thermo Fisher,PA5-40294 IRE1α,CST,3294T p-IRE1α,Abcam,ab48187 ATF6,Proteintech,24169-1-AP ATF4,Abcam,ab270980 eIF2α,CST,5324 p-eIF2α,CST,3597 xBP-1(s),CST,"12,782" CHOP,CST,2895T Flag,CST,"#14,793" Anti-rabbit IgG,CST,7074P2 Anti-mouse IgG,CST,7076P2 β-actin,CST,4970T Details

(3) Tetramethylthiuram disulfide induces stress granules and DNA damage through oxidative stress in human lung epithelial cellsAnim Cells Syst (Seoul)March 13, 2026Ma Lin, Sangsoo Lee, Jiyun Gwak, Jihyun Cha, Seongjin Hong, Eun-Mi Kim, Kee K. KimSanta Cruz Biotechnology, Dallas, TX, USA; Cat# sc-133132), anti-phospho-eIF2α (1:1000, Cell Signaling Technology; Cat# 3597), anti-GAPDH (1:5000, Biodesign, Memphis, TN, USA; Cat# H86504M), and anti-γH2AX (1:1000, Abcam, Cambridge,

(4) Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer CellsAdvanced ScienceMarch 1, 2026Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu(#18665S), XBP‐1s (#12782S), IRE1α (#3294T), BiP (#3177T), PERK (#5683T), eIF2α (#5324T), p‐eIF2α (#3597S), p62 (#5114), LC3B (#2775S), and β‐actin (#3700S), were purchased from Cell Signaling Technology. Porimin

(5) Citrate clearance is a major function of aconitase 2 in the canonical TCA cycleCellFebruary 27, 2026Abigail Xie, Julia S. Brunner, Sangita Chakraborty, Angela M. Montero, Anna E. Bridgeman, Katrina I. Paras, Ruobing Cui, Maider Fagoaga-Eugui, Monika Komza, Paige K. Arnold, et al.(12406–1-AP, ProteinTech), anti-ATF4 (11815s, Cell Signaling Technology), anti-phospho-eIF2α (Ser51, 3597, Cell Signaling Technology), anti-eIF2α (9721S, Cell Signaling Technology), anti-SLC13A2 (21722–1-AP,

(6) Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiationiScienceFebruary 20, 2026Stephanie G. Moreno, Federica Ferri, Daniel Lewandowski, Vilma Barroca, Saiyiramii Devanand, Nathalie Dechamps, Paul-Henri Romeo, Nathalie Gault5324 (clone D7D3); RRID:AB_10692650 Phospho-eIF2α (Ser151) Rabbit mAb,Cell Signaling Technology,Cat# 3597 (clone 119A11); RRID:AB_390740 Vinculin XP rabbit mAb,Cell Signaling Technology,Cat# 13901 (clone E1E9V);

(7) A dose-dependent switch in translation capacity controls the transcription factor response to H 2 O 2 stressbioRxivJanuary 31, 2026Chance Parkinson, Woody March-Steinman, Elizabeth Jose, Lisa Shanks, Andrew L. PaekCell Signaling Cat# 2661S (1:200). Anti-Phospho-eIF2a (S51) (119A11) rabbit mAb from Cell Signaling Cat# 3597S (1:200). Anti-Phospho-S6 Ribosomal Protein (S235/236) rabbit mAb from Cell Signaling Cat# 2211S (1:500).

(8) AGPAT2 acts at the crossroads of lipid biosynthesis and DRP1-mediated ER morphogenesisNat CommunDecember 12, 2025Yoshihiro Adachi, Mauricio Torres, Allen H. Hunter, Woo Jung Cho, Meixia Pan, Xianlin Han, Guangwei Du, Ling Qi, Miho Iijima, Hiromi SesakiCell Signaling Technology), eIF2α (1:1000, 2103, Cell Signaling Technology), phospho-eIF2α (1:1000, 3597, Cell Signaling Technology), CHOP (1:1000, 2895, Cell Signaling Technology), GFP31,72 and actin (1:1000,

(9) Integrated stress response-mediated metabolic reprogramming drives hepatic stellate cell activation and liver fibrosis via the noncanonical EIF3d-ATF4-S100P signaling pathwayRedox BiologyDecember 1, 2025Simin Yang, Hongli Zhang, Xiaoyan Sun, Zhengyang Chen, Zhentian Nie, Yuting Li, Xiaohan Liu, Yawei Kong, Ziyu Wang, Wenjing Zai, et al.Materials and reagents Antibodies used were EIF3d (Proteintech, 10219-1-AP), p-eIF2a (Cell Signaling, 3597L), ATF4 (Cell Signaling, 11815S), phospho-SAPK/JNK (Thr183/Tyr185) (Cell Signaling, 9251S), SAPK/JNK

(10) A retrograde, non-canonical integrated stress response cascade maintains synaptic strength under amino acid deprivationCell ReportsNovember 25, 2025Megumi Mori, Grant Kauwe, Ammar Aly, Edward H. Liao, Gary Scott, A. Pejmun HaghighiRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies anti-phospho-eIF2α,Cell Signaling,Cat#3597; RRID:AB_390740 anti-non-phospho-eIF2α,abcam,Cat#ab26197; RRID:AB_2096478 anti-Actin,Sigma-Aldrich,Cat#MAB1501;

(11) Atovaquone-induced oxidative stress activates the pentose phosphate pathway and Immunogenic cell death in ovarian cancerScientific ReportsNovember 24, 2025Mayra Betancourt Ponce, Nicha Boonpattrawong, Alexander J. Fagan, Michael Newton, Manish Patankar, Lisa Barroilhetantibodies. The primary antibodies used were against phosphorylated EIF2α (Cell Signaling Technology, #3597), EIF2α (Cell Signaling Technology, #9722), CHOP (Cell Signaling Technology, #2895), G6PD (Cell Signaling

(12) Host Translational Control by Stress Granules Promotes Mycobacterium tuberculosis PathogenesisMedComm (2020)November 10, 2025Jaewhan Kim, Sang‐Hun Son, Ji‐Ae Choi, Junghwan Lee, Seoyeon Jo, Soo‐Na Cho, Doan Tam Nguyen, Doyi Son, Kee K. Kim, Chang‐Hwa Song(CST, 4970), rabbit anti‐Drp1 (CST, 8570), rabbit anti‐Eif2α (CST, 5324), rabbit anti‐Eif2α‐pS51 (CST, 3597), rabbit anti‐Eif4e (CST, 2067), rabbit anti‐G3bp1 (CST, 61559), rabbit anti‐mTOR‐pS2448 (CST, 5536),

(13) ER stress tolerance is regulated by copper-dependent PERK kinase activityCell reportsOctober 28, 2025Bond Newton SE, Shi X, Beratan NR, Perhacs J, Arya JK, Bond MK, Gidalevitz T, Akay-Espinoza C, Brady DC, Jordan-Sciutto KL.Cat#31444 Phospho-eIF2α (Ser51) (119A11) Rabbit mAb,Cell Signaling Technologies,RRID:AB_390740; Cat#3597 12G10 anti-alpha-tubulin,Developmental Studies Hybridoma Bank,RRID:AB_1157911; Cat:12G10 ,, Bacterial

(14) Targeting GPX2 to disrupt lipid homeostasis and enhance cisplatin sensitivity in diffuse gastric cancerCell Death DiscovOctober 27, 2025Yanmei Zhu, Yichun Ma, Wenying Li, Yani Pan, Yue Wang, Qiange Ye, Yinya Pan, Ying Xiang, Ping Jiang, Yi Fang, et al.9548T); BCL2(PTM BIO, A18415); c-PARP1 (PTM BIO, PTM-7466); GRP78/BIP (ABclonal, A0241); p-eIF2α (CST, 3597S); p-PERK (ABclonal, AP0086); e-IRE1a (ABclonal, AP1146); XBP1s (ABclonal, A17007). Proliferation assay Colony

(15) Endoplasmic reticulum-resident protein DNAJC10 inhibits glioblastoma metastasis by suppressing XBP-1s-driven EGFR transcriptionMolecular BiomedicineOctober 24, 2025Erdi Zhao, Yue Yu, Yingli Gao, Teng Li, Shiyu Hao, Meiyang Chen, Ming Xu, Sinkemani Arjun, Chunyan Yang, Yancun Yin, et al.XBP-1s (40,435), N-Cadherin (13,116), Anti-ZO-1 (13,663), Vinmentin (5741), EIF2α (5324), P-EIF2α S51 (3597), H3K4me3(9751), H3K4me1(5326), P300 (54,062) and H3K27ac (8173) are derived from Cell Signaling Technology.

(16) IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancerCell Death DisOctober 6, 2025Yuan Luo, Mengqi Sun, Lei Chang, Zinan He, Xinghang Zhou, Yaming Yuan, Huijuan Sun, Shiqi Luo, Jinyan Huang, Hongkun Wu, et al.1:1000), cGAS (Cell Signaling 31659; 1:2000), eIF2α (Cell Signaling 9722; 1:2000), p-eIF2α (Cell Signaling 3597; 1:1000), γ-H2AX (Abclonal AP0099; 1:2000), OXPHOS (Abcam ab110413; 1:5000), VDAC (Proteintech 10866-1-AP;

(17) Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in micebioRxiv : the preprint server for biologySeptember 4, 2025Calubag MF, Ademi I, Green CL, Jayarathne HSM, Manchanayake DNH, Le SM, Lialios P, Breuer LE, Yakar S, Babygirija R, et al.(9202), pS240/244-S6 (2215), S6 (2217), pThr37/46 4E-BP1 (2855), 4E-BP1 (9644), eIF2α (5324), pS51-eIF2α (3597), AMPKa (5831), pAMPKa (4188), Beclin-1 (3495), LC3A/B (12741), GAPDH (2118), and β-tubulin (2146) were

(18) The endoplasmic reticulum stress-ferroptosis reciprocal signaling orchestrates anti-tumor effect of anlotinib in anaplastic thyroid cancerCancer Cell IntAugust 21, 2025Yehao Guo, Juyong Liang, Lingling Ding, Jiajun Wu, Weidong Teng, Jiafeng Wang, Liehao Jiang, Zhuo Tanrabbit anti-PERK (#5683, 1:1000), rabbit anti-BiP (#3177, 1:1000), and rabbit anti-phospho-eIF2α (#3597, 1:1000) from Cell Signaling Technology, USA; and rabbit anti-eIF2α (AF6087, 1:1000) from Affinity,

(19) Genetic mapping of lifespan and mitochondrial stress response in C. elegansResearch SquareJuly 31, 2025Johan Auwerx, Xiaoxu Li, Weisha Li, Arwen Gao, YunYun Zhu, Elena Katsyuba, Katherine Overmyer, Terytty Yang Li, Ziwen Wang, Luc Legon, et al.inhibitors, as described previously15. For western blotting, the antibodies used were: P-EIF2α (Cat. 3597, CST, 1:800), Tubulin (Cat. T5168, Sigma, 1:2000), ASNS (Santa Cruz, Cat. sc-365809, 1:1000), EIF2α

(20) Activation of the integrated stress response and loss of cFLIPL under glutamine limitation induce IL-8 gene expression and secretion in glutamine-dependent tumor cellsCell Death DiscovJuly 19, 2025Rocío Mora-Molina, F. Javier Fernández-Farrán, Abelardo López-Rivas, Carmen Palacios7F10 (ALX-804-961-0100) was obtained from Enzo Life Sciences (NY, USA). Anti-p-eIF2α (S51) (119A11) (3597), anti-eIF2α (D7D3) (5324), anti-CHOP (D46F1) (5554) and anti-TAK1 (4505) antibodies were purchased

Be the First to Write a Review!

Phospho-eIF2alpha (Ser51) (119A11) Rabbit mAb

Phospho-eIF2alpha (Ser51) (119A11) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (374)

Reviews

Phospho-eIF2alpha (Ser51) (119A11) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map