Histone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody (Clone 11D3) 17939 from Cayman Chemical

Product Specs
ItemHistone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody (Clone 11D3)
CompanyCayman Chemical
Price $440.00Supplier Page View Company Product Page
Catalog Number17939
Quantity100 µg
ApplicationsELISA, WB
Format100 µg protein G-purified IgG
ReactivityHuman; other species not tested
TargetHistone H3
IsotypeIgG1K
Clone11D3
HostMouse
Antibody TypePrimary
Molecular Weight~16 kDa
ImmunogenHistone H3 peptide with citrulline at R2, R8, and R17
NCBI Full Gene NameH3 clustered histone 1
NCBI Gene AliasesH3/A, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, HIST1H3A
ClonalityMonoclonal
Research AreaAutoimmunity, Cancer, Citrullinated, Citrullination, Epigenetics, Transcription, & Translation, Histones/Histone Peptides, Immunology & Inflammation, Innate Immunity, Multiple Sclerosis, NETosis, Neurodegenerative Disorders, Neuroscience, Rheumatoid Arthritis, Sepsis/Shock, Writers
Storage-20
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Bilirubin reduces mortality in sepsis models by inhibiting NOX2-mediated formation of neutrophil extracellular trapsRedox RepDecember 31, 2026Sang-Jin Kim, Chang Woo Ko, Wan-Seo Kim, Yeon Jun Kang, Chul-Hwan Lee, Won-Woo Lee, Jong-Wan Park(Danvers, MA); anti-NOX2 antibody (ab80897, 1:2000) from Abcam (Cambridge, UK); Anti-H3cit antibody (17939, 1:2000) from Cayman Chemical (Ann Arbor, MI); anti-FLAG antibody (F7425, 1:2000) from Sigma-Aldrich

(2) Human urine-derived stem cells alleviate psoriasis by suppressing JAK2/STAT3 pathway-mediated macrophage polarizationStem Cell Research & TherapyDecember 17, 2025You-Qiong Zhuo, Qi-Ming Huang, Hao-Cheng Gu, Ling-Fang Wang, Dilnuer Tula, Xing-Yu Wei, Zhou-Hang Zhang, Ke-Yu Deng, Hong-Bo Xin(1:500, 28463-1-AP, Proteintech), anti-Ly6G (1:400, WLH4318, Wanleibio, China) and anti-Cit-H3 (1:200, 17939, Cayman, USA). The samples were subjected to a one-hour incubation in the dark at room temperature with

(3) Formation of neutrophil extracellular traps in the early stages exacerbate the healing process by regulating macrophage polarization in Achilles tendon-bone injuryJ Tissue EngAugust 19, 2025Yiqin Zhou, Xiaolei Yang, Dawei Niu, Peiliang Fu, Qirong Qian, Qi Zhoufor 6 min. Cells were stained with CD11b (982604, Biolegend), CD66b (392904, Biolegend), and citH3 (17939, Cayman Chemical) and analyzed as above. Cell cultures Bone marrow-derived macrophages (BMDMs) were

(4) Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseationCell Host & MicrobeDecember 11, 2024Chanchal Sur Chowdhury, Rachel L. Kinsella, Michael E. McNehlan, Sumanta K. Naik, Daniel S. Lane, Priyanka Talukdar, Asya Smirnov, Neha Dubey, Ananda N. Rankin, Samuel R. McKee, et al.MA5-16808 Histone H3 (Citrullinated R2 + R8 + R17) monoclonal antibody clone 11D3,Cayman Chemical Company,Cat# 17939 Mouse monoclonal antibody CD11c clone 5D11,Leica Biosystems,Cat# NCL-L-CD11c-563 Interferon alpha-2

(5) Leukocyte filtration and leukocyte modulation therapy during extracorporeal cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrestScientific reportsJune 7, 2024VanZalen JJ, Nakashima T, Phillips A, Hill JE, Westover AJ, Lou L, Liao J, Mergos J, Fogo G, Sanderson TH, et al.4 °C overnight with the following primary antibodies: mouse anti-citrullinated Histone H3 antibody (17939, Cayman Chemical, Ann Arbor, MI) and rabbit anti-von Willebrand factor antibody (NB600586, NOVUS BIOLOGICALS,

(6) Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivityIUCrJMay 1, 2024Fanomezana M. Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumontr.p.m. shaking, followed by incubation with the primary antibody (anti-citrullinated H3: Cayman, No. 17939) diluted 1:500 in 1% BSA and 0.05% Tween 20 in PBS, and secondary antibody (HRP-conjugated anti-mouse:

(7) Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivityIUCrJApril 24, 2024Fanomezana M. Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumontr.p.m. shaking, followed by incubation with the primary antibody (anti-citrullinated H3: Cayman, No. 17939) diluted 1:500 in 1% BSA and 0.05% Tween 20 in PBS, and secondary antibody (HRP-conjugated anti-mouse:

(8) Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaquesCellJanuary 21, 2021Hoang TN, Pino M, Boddapati AK, Viox EG, Starke CE, Upadhyay AA, Gumber S, Nekorchuk M, Busman-Sahay K, Strongin Z, et al.for 1 hour. Primary antibody staining was performed for citrullinated H3 (Cayman Chemical, Cat. No. 17939, 1:50) overnight at 4°C. Slides were then incubated with Alexa Fluor 633 anti-mouse IgG secondary antibody

(9) Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasmaJournal of Thrombosis and HaemostasisOctober 1, 2020Charlotte Thålin et al.ng/mL (IQR 62.3–164.3).,30 "CitH3 ELISA kit (Cayman #501602). Ab: monoclonal H3R2,8,17Cit (Cayman #17939). Ab specificity tested against peptide arrays. Calibration standard: in vitro enzymatically citrullinated

(10) Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft DysfunctionAmerican journal of respiratory cell and molecular biologyMarch 1, 2020Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, et al.CA) or anti-citrullinated histone-3 primary antibodies (mouse: ab5103, Abcam, Burlingame, CA; human: 17939, Cayman Chemical Company, Ann Arbor, MI) and an anti-DNA-HRP antibody (Cell Death Detection ELISAplus

(11) Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial ErosionCirculation ResearchJune 22, 2018Grégory Franck et al.monoclonal mAb 11D1 mouse anti-Histone H3 (citrullinated R2+R8+R17, N-Terminal sequence; Cayman number 17939), washed, and incubated with mouse plasma samples. After washing, the wells were incubated with biotinylated

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Histone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody (Clone 11D3) from Cayman Chemical

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Cayman Chemical

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Histone H3 (Citrullinated R2 + R8 + R17) Monoclonal Antibody (Clone 11D3) from Cayman Chemical

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