CD25/IL-2R alpha Antibody (Basiliximab) [DyLight 488] - Chimeric NBP2-75902G from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemCD25/IL-2R alpha Antibody (Basiliximab) [DyLight 488] - Chimeric
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberNBP2-75902G
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Gene AliasesCD25, IDDM10, IL2R, IMD41, TCGFR, p55
NCBI Full Gene Nameinterleukin 2 receptor subunit alpha
Format50mM Sodium Borate
Research AreaAdaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
ReactivityHu, CyMk, RhMk
ClonalityMonoclonal
ApplicationsWB, FCM, ICC, IF, IHC, Neut
ImmunogenBasiliximab was prepared by immunizing BALB/c mice with CTC 16 cells
HostHuman
CloneBasiliximab
IsotypeIgG1 Kappa
TargetCD25/IL-2R alpha
PurityProtein A purified
Conjugate/TagDyLight 488
Quantity0.1 ml

Specifications/Features

Available conjugates: Available conjugates: DyLight 488

Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.

Sizes Available: 0.1 ml

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