The GAPDH Monoclonal Antibody from Bioassay Technology Laboratory is a Mouse Monoclonal antibody. This antibody recognizes Human, Mouse, Rat, Bacteria/Archaea, Bovine, C. elegans/Worm, Donkey, Feline, Guinea Pig, Hamster, Horse, Mollusc, Non-Human Primate, Plant, Reptile, Rabbit, Virus, Yeast/Fungi, Zebrafish/Fish, Other Invertebrate, and Other Mammalian antigen. The GAPDH Monoclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri