Rabbit Anti-Bcl-2 Antibody MBS4380206 from MyBioSource.com

Product Specs
ItemRabbit Anti-Bcl-2 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380206
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesBcl-2, PPP1R50
NCBI Full Gene NameBCL2, apoptosis regulator
ApplicationsWB, FCM, IF, IHC-p
ImmunogenThis antibody recognizes a protein of 25-26kDa, identified as the bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative
HostRabbit
CloneBCL2/1878R
Molecular Weight25-26kDa
IsotypeIgG
TargetBcl-2
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Conjugate/TagUnconjugated
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)