Rabbit Anti-CD1a/HTA1 Antibody MBS4380303 from MyBioSource.com

Product Specs
ItemRabbit Anti-CD1a/HTA1 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380303
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesR4, FCB6, HTA1, T6, CD1
NCBI Full Gene NameCD1a molecule
ApplicationsFCM, IF, IHC-p
ImmunogenAt least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa)
HostRabbit
CloneC1A/1506R
Molecular Weight49kDa
IsotypeIgG
TargetCD1a/HTA1
Format200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Conjugate/TagUnconjugated
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)