MyBioSource.com's MTHFD1 Mouse mAb is a Mouse monoclonal antibody. The MTHFD1 Mouse mAb Antibody was generated using MTHFD1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunoprecipitation, and Western Blot.
Description
This gene encodes a protein that possesses three distinct enzymatic activities, 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain