Rabbit Anti-Interleukin 10 Antibody MBS4380606 from MyBioSource.com

Product Specs
ItemRabbit Anti-Interleukin 10 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380606
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsImmunohistology (Formalin-Fixed)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified by Protein A. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ReactivityHuman. Others not known
TargetInterleukin 10 (IL10)
IsotypeIgG
Molecular Weight20kDa (Monomer); 37kDa (Dimer)
CloneIL10/2651R
HostRabbit
ImmunogenInterleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
NCBI Full Gene Nameinterleukin 10
NCBI Gene AliasesIL10A, TGIF, GVHDS, IL-10, CSIF
ClonalityMonoclonal