The Involucrin antibody from MyBioSource.com is a Mouse Monoclonal antibody to Involucrin, and IVL. This antibody recognizes Human antigen. The Involucrin antibody has been shown to work in the following applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reducedin severe dysplasias of the larynx and cervix