The POGZ Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Pogz. This antibody recognizes Human antigen. The POGZ Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.
Subunit Structure: Interacts with CBX1, CBX3, MAD2L2 and CHAMP1. Interacts with CBX5; POGZ competes with PXVXL motif-containing proteins such as INCENP and TRIM28 for interaction with CBX5. Interacts with PSIP1 isoform 1