MyBioSource.com's CDKA2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Immunohistochemistry.
Description
Description: CDK2AP2 Belongs to the CDK2AP family. Note: This description may include information from UniProtKB.
Function: Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148).
Subunit Structure: Interacts with CDK2AP1 (PubMed:14985111). Interacts with CDK2 (PubMed:23781148). Interacts with MAPK1 (By similarity).
Post-translational Modifications: Phosphorylated by MAPK1 and CDK2.
Similarity: Belongs to the CDK2AP family