Rabbit Anti-HCG-beta Antibody MBS439863 from MyBioSource.com

Product Specs
ItemRabbit Anti-HCG-beta Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS439863
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Full Gene Namechorionic gonadotropin subunit beta 8
ApplicationsImmunohistochemistry-paraffin (IHC-p)
ImmunogenThis MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the and subunits. The subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior
HostRabbit
CloneHCGb/1996R
Molecular Weight22kDa
IsotypeIgG
TargetHCG-beta
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Conjugate/TagUnconjugated
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)