The CEACAM5 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CEACAM5. This antibody recognizes Human, Mouse, and Rat antigen. The CEACAM5 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Expression of CEA is correlated with tumerogenicity (1), and it has been shown to play a role in cell migration, adhesion and invasion in culture cells, as well as in metastasis in vivo (2).
Function: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
Subunit Structure: Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Post-translational Modifications: Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Similarity: Belongs to the immunoglobulin superfamily. CEA family