The Rabbit Anti-I kappaB epsilon Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NFKBIE. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-I kappaB epsilon Antibody has been shown to work in the following applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Description: kB-epsilon Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit.
Function: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Subunit Structure: Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit.
Post-translational Modifications: Serine phosphorylated; followed by proteasome-dependent degradation.
Similarity: Belongs to the NF-kappa-B inhibitor family