The Rabbit Anti-Insulin Receptor Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to INSR, and Insulin Receptor. This antibody recognizes Human antigen. The Rabbit Anti-Insulin Receptor Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, binds IGF1