The TAS2R Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Thromboxane A2 Receptor. This antibody recognizes Human, Mouse, and Rat antigen. The TAS2R Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Function: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.
Subunit Structure: Interacts with RPGRIP1L. Interacts with PSMA3. Interacts with RACK1; the interaction regulates TBXA2R cell surface expression.
Similarity: Belongs to the G-protein coupled receptor 1 family