MyBioSource.com's Rabbit Anti-IL-8R beta/CDw128 beta Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot. The Rabbit Anti-IL-8R beta/CDw128 beta Antibody was generated using CXCR2 as the antigen and it reacts with Human, and Mouse.
Description
Function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Post-translational Modifications: Phosphorylated upon ligand binding; which is required for desensitization.
Similarity: Belongs to the G-protein coupled receptor 1 family