The LETM1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to LETM1. This antibody recognizes Human, Mouse, and Rat antigen. The LETM1 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Function: Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed:19797662). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306). Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248).
Subunit Structure: Homohexamer (By similarity). Can form 2 complexes: a major (300 kDa) and a minor complex (500-600 kDa) (PubMed:18628306). Interacts with BCS1L (PubMed:18628306).
Similarity: Belongs to the LETM1 family