MyBioSource.com's Matriptase Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot. The Matriptase Antibody was generated using ST14 as the antigen and it reacts with Human, and Mouse.
Description
Function: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
Subunit Structure: Interacts with CDCP1. May interact with TMEFF1.
Similarity: Belongs to the peptidase S1 family