MyBioSource.com's PI4KB Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PI4KB Antibody was generated using PI4KB as the antigen and it reacts with Human.
Description
Function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity).
Subunit Structure: Interacts with ARF1 and ARF3 in the Golgi complex, but not with ARF4, ARF5 or ARF6 (PubMed:17555535). Interacts with NCS1/FREQ in a calcium-independent manner. Interacts with CALN1/CABP8 and CALN2/CABP7; in a calcium-dependent manner; this interaction competes with NCS1/FREQ binding (By similarity). Interacts with ACBD3 (PubMed:27009356, PubMed:27989622, PubMed:23572552). Interacts with YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ, YWHAZ and SFN (PubMed:23572552).
Similarity: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily