The NFκB-p65(Phospho Thr505) Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The NFκB-p65(Phospho Thr505) Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor: NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL: RELA: or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene: RELA. Four transcript variants encoding different isoforms have been found for this gene