Anti-Collagen I antibody (Biotin) GTX26577 from GeneTex

Description

GeneTex's Anti-Collagen I antibody (Biotin) is a Rabbit Polyclonal antibody. The Anti-Collagen I antibody (Biotin) was generated using collagen type I alpha 1 chain, EDSARTH1, EDSC, OI1, OI2, OI3, OI4 as the antigen. The Anti-Collagen I antibody (Biotin) from GeneTex is a Rabbit Polyclonal antibody to Collagen I. The Anti-Collagen I antibody (Biotin) Recognizes Human, Mouse, Rat. The Anti-Collagen I antibody (Biotin) has been validated for the following Applications: WB, ICC/IF, IHC-P, FCM, Dot, Multiplexing

Product Specs
ItemAnti-Collagen I antibody (Biotin)
CompanyGeneTex
Price $419.00Supplier Page
Catalog NumberGTX26577
ClonalityPolyclonal
Quantity50 µg
TargetCollagen I
Format20mM Potassium Phosphate, 150mM NaCl, 1% BSA, 0.01% Sodium azide
Antibody TypePrimary Antibodies
IsotypeIgG
ReactivityHuman, Mouse, Rat
HostRabbit
ApplicationsWB, ICC/IF, IHC-P, FCM, Dot, Multiplexing
Conjugate/TagBiotin
Concentration1mg/ml
PurityPurified by antigen-affinity chromatography
ImmunogenCollagen Type I from human and bovine placenta
Research AreaCancer, Development
NCBI Full Gene Namecollagen type I alpha 1 chain
NCBI Gene Aliasescollagen type I alpha 1 chain, EDSARTH1, EDSC, OI1, OI2, OI3, OI4, CAFYD, EDSC, EDSARTH1, OI4, OI3, OI2, OI1
Gene NameCOL1A1
Molecular Weight139

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Questions and Answers

What species does this antibody recognize, and is it suitable for my research on collagen-related diseases?

The Anti-Collagen I antibody (Biotin) recognizes Collagen I from Human, Mouse, Rat, and Bovine species. Given its specificity for Collagen I, it may be suitable for research on collagen-related diseases, including various forms of osteogenesis imperfecta and other connective tissue disorders.

Can I use this antibody for immunohistochemistry, and what kind of samples would be appropriate?

Yes, this antibody has been validated for use in immunohistochemistry (IHC-P). It is appropriate for use with tissue samples that express Collagen I, such as skin, bone, and cartilage tissues, which are commonly studied in developmental biology and cancer research.

How does the biotin tag affect the application of this antibody in my experiments?

The biotin tag allows for enhanced detection methods, such as using streptavidin-conjugated detection systems in techniques like ELISA and flow cytometry (FACS). This can improve sensitivity and specificity in your assays, making it a valuable tool for quantifying Collagen I levels.

Is there any information on the purity and concentration of this antibody that would be relevant for my experimental design?

The Anti-Collagen I antibody (Biotin) is purified by antigen-affinity chromatography and has a concentration of 1 mg/ml. This high level of purity ensures minimal background noise in your experiments, which is crucial for obtaining reliable and reproducible results.