The Rabbit Anti-PI 3 Kinase Class 3 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PIK3C3. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-PI 3 Kinase Class 3 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed: 20643123, PubMed: 20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity)