The Rabbit Anti-Topoisomerase II alpha Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to TOP2A. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Topoisomerase II alpha Antibody has been shown to work in the following applications: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity)