MyBioSource.com's Rabbit Anti-Annexin A2 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Annexin A2 Antibody was generated using Annexin A2, and ANXA2 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed: 18799458, PubMed: 24808179, PubMed: 22848640)